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Phase separation-deficient TDP43 remains functional in splicing
Intrinsically disordered regions (IDRs) are often fast-evolving protein domains of low sequence complexity that can drive phase transitions and are commonly found in many proteins associated with neurodegenerative diseases, including the RNA processing factor TDP43. Yet, how phase separation contrib...
Enregistré dans:
| Publié dans: | Nat Commun |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6814767/ https://ncbi.nlm.nih.gov/pubmed/31653829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12740-2 |
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