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Phase separation-deficient TDP43 remains functional in splicing
Intrinsically disordered regions (IDRs) are often fast-evolving protein domains of low sequence complexity that can drive phase transitions and are commonly found in many proteins associated with neurodegenerative diseases, including the RNA processing factor TDP43. Yet, how phase separation contrib...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6814767/ https://ncbi.nlm.nih.gov/pubmed/31653829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12740-2 |
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