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Development of In Vitro–In Vivo Correlation for Upadacitinib Extended-Release Tablet Formulation

Upadacitinib is a selective Janus Kinase 1 inhibitor which is being developed for the treatment of several inflammatory diseases including rheumatoid arthritis. Upadacitinib was evaluated in Phase 3 studies as an oral extended-release (ER) formulation administered once daily. The purpose of this stu...

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Detalhes bibliográficos
Publicado no:AAPS J
Main Authors: Mohamed, Mohamed-Eslam F., Trueman, Sheryl, Othman, Ahmed A., Han, Jian-Hwa, Ju, Tzuchi R., Marroum, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814631/
https://ncbi.nlm.nih.gov/pubmed/31654328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-019-0378-y
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