Biomimetic Synthesis of Meroterpenoids by Dearomatization- Driven Polycyclization

A biomimetic route to farnesyl pyrophosphate and dimethyl orsellinic acid (DMOA)-derived meroterpenoid scaffolds has yet to be reported despite great interest from the chemistry and biomedical research communities. A concise synthetic route with the potential to access DMOA-derived meroterpenoids is...

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Veröffentlicht in:Angew Chem Int Ed Engl
Hauptverfasser: Powers, Zachary, Scharf, Adam, Cheng, Andrea, Yang, Feng, Himmelbauer, Martin, Mitsuhashi, Takaaki, Barra, Lena, Taniguchi, Yoshimasa, Kikuchi, Takashi, Fujita, Makoto, Abe, Ikuro, Porco, John A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814491/
https://ncbi.nlm.nih.gov/pubmed/31515901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201910710
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