Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis

Non-heme iron and α-ketoglutarate (αKG) oxygenases catalyze remarkably diverse reactions using a single ferrous ion cofactor. A major challenge in studying this versatile family of enzymes is to understand their structure–function relationship. AusE from Aspergillus nidulans and PrhA from Penicilliu...

Full description

Saved in:
Bibliographic Details
Published in:Nat Commun
Main Authors: Nakashima, Yu, Mori, Takahiro, Nakamura, Hitomi, Awakawa, Takayoshi, Hoshino, Shotaro, Senda, Miki, Senda, Toshiya, Abe, Ikuro
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760668/
https://ncbi.nlm.nih.gov/pubmed/29317628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02371-w
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items