Epigenetic modifier-induced biosynthesis of novel fusaric acid derivatives in endophytic fungi from Datura stramonium L.

ABSTRACT: The treatment of fungi with DNA methyltransferase (DNMT) and/or histone deacetylase (HDAC) inhibitors is a promising way to activate secondary metabolite biosynthetic pathways that are dormant under normal conditions. In this study, we included an HDAC inhibitor, suberoylanilide hydroxamic...

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Main Authors: Chen, Han-Jing, Awakawa, Takayoshi, Sun, Jie-Yin, Wakimoto, Toshiyuki, Abe, Ikuro
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2013
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131616/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13659-013-0010-2
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