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Molecular basis for the plasticity of aromatic prenyltransferases in hapalindole biosynthesis

Aromatic prenyltransferases (PTases) are enzymes that catalyze Friedel–Crafts reactions between aromatic compounds and isoprenoid diphosphates. In hapalindole biosynthesis, the aromatic PTases AmbP1 and AmbP3 exhibit surprisingly plastic selectivities. AmbP1 not only transfers the geranyl group on t...

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Dades bibliogràfiques
Publicat a:Beilstein J Org Chem
Autors principals: Awakawa, Takayoshi, Abe, Ikuro
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632223/
https://ncbi.nlm.nih.gov/pubmed/31354873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.157
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