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Molecular basis for the plasticity of aromatic prenyltransferases in hapalindole biosynthesis

Aromatic prenyltransferases (PTases) are enzymes that catalyze Friedel–Crafts reactions between aromatic compounds and isoprenoid diphosphates. In hapalindole biosynthesis, the aromatic PTases AmbP1 and AmbP3 exhibit surprisingly plastic selectivities. AmbP1 not only transfers the geranyl group on t...

詳細記述

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書誌詳細
出版年:Beilstein J Org Chem
主要な著者: Awakawa, Takayoshi, Abe, Ikuro
フォーマット: Artigo
言語:Inglês
出版事項: Beilstein-Institut 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632223/
https://ncbi.nlm.nih.gov/pubmed/31354873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.157
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