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Molecular basis for the plasticity of aromatic prenyltransferases in hapalindole biosynthesis
Aromatic prenyltransferases (PTases) are enzymes that catalyze Friedel–Crafts reactions between aromatic compounds and isoprenoid diphosphates. In hapalindole biosynthesis, the aromatic PTases AmbP1 and AmbP3 exhibit surprisingly plastic selectivities. AmbP1 not only transfers the geranyl group on t...
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| Udgivet i: | Beilstein J Org Chem |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Beilstein-Institut
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6632223/ https://ncbi.nlm.nih.gov/pubmed/31354873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.157 |
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