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Molecular basis for the plasticity of aromatic prenyltransferases in hapalindole biosynthesis

Aromatic prenyltransferases (PTases) are enzymes that catalyze Friedel–Crafts reactions between aromatic compounds and isoprenoid diphosphates. In hapalindole biosynthesis, the aromatic PTases AmbP1 and AmbP3 exhibit surprisingly plastic selectivities. AmbP1 not only transfers the geranyl group on t...

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Detaylı Bibliyografya
Yayımlandı:Beilstein J Org Chem
Asıl Yazarlar: Awakawa, Takayoshi, Abe, Ikuro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Beilstein-Institut 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632223/
https://ncbi.nlm.nih.gov/pubmed/31354873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.157
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