Branched chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control

Elevated branched chain amino acids (BCAAs) are associated with obesity and insulin resistance. How long-term dietary BCAAs impact late-life health and lifespan is unknown. Here, we show that when dietary BCAAs are varied against a fixed, isocaloric macronutrient background, long-term exposure to hi...

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Bibliografiske detaljer
Udgivet i:Nat Metab
Main Authors: Solon-Biet, Samantha M, Cogger, Victoria C, Pulpitel, Tamara, Wahl, Devin, Clark, Ximonie, Bagley, Elena, Gregoriou, Gabrielle C, Senior, Alistair M, Wang, Qiao-Ping, Brandon, Amanda E, Perks, Ruth, O’Sullivan, John, Koay, Yen Chin, Bell-Anderson, Kim, Kebede, Melkam, Yau, Belinda, Atkinson, Clare, Svineng, Gunbjorg, Dodgson, Timothy, Wali, Jibran A, Piper, Matthew D W, Juricic, Paula, Partridge, Linda, Rose, Adam J, Raubenheimer, David, Cooney, Gregory J, Le Couteur, David G, Simpson, Stephen J
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814438/
https://ncbi.nlm.nih.gov/pubmed/31656947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-019-0059-2
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