Enhanced Bruton’s tyrosine kinase in B-cells and autoreactive IgA in patients with idiopathic pulmonary fibrosis

RATIONALE: Idiopathic Pulmonary Fibrosis (IPF) is thought to be triggered by repeated alveolar epithelial cell injury. Current evidence suggests that aberrant immune activation may contribute. However, the role of B-cell activation remains unclear. We determined the phenotype and activation status o...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Heukels, Peter, van Hulst, Jennifer A. C., van Nimwegen, Menno, Boorsma, Carian E., Melgert, Barbro N., von der Thusen, Jan H., van den Blink, Bernt, Hoek, Rogier A. S., Miedema, Jelle R., Neys, Stefan F. H., Corneth, Odilia B. J., Hendriks, Rudi W., Wijsenbeek, Marlies S., Kool, Mirjam
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814043/
https://ncbi.nlm.nih.gov/pubmed/31651327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1195-7
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