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Targeting Bruton’s Tyrosine Kinase in Inflammatory and Autoimmune Pathologies
Bruton’s tyrosine kinase (BTK) was discovered due to its importance in B cell development, and it has a critical role in signal transduction downstream of the B cell receptor (BCR). Targeting of BTK with small molecule inhibitors has proven to be efficacious in several B cell malignancies. Interesti...
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| Publicado no: | Front Cell Dev Biol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8213343/ https://ncbi.nlm.nih.gov/pubmed/34150760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.668131 |
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