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Role of Bruton’s tyrosine kinase in B cells and malignancies
Bruton’s tyrosine kinase (BTK) is a non-receptor kinase that plays a crucial role in oncogenic signaling that is critical for proliferation and survival of leukemic cells in many B cell malignancies. BTK was initially shown to be defective in the primary immunodeficiency X-linked agammaglobulinemia...
Gespeichert in:
| Veröffentlicht in: | Mol Cancer |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5817726/ https://ncbi.nlm.nih.gov/pubmed/29455639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0779-z |
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