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Heterobiaryl synthesis by contractive C-C coupling via P(V) intermediates
Heterobiaryls composed of pyridine and diazine rings are key components of pharmaceuticals and are often central to pharmacological function. We present an alternative approach to metal-catalyzed cross-coupling to make heterobiaryls using contractive phosphorus C–C couplings, also termed phosphorus...
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| Publicado no: | Science |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6814017/ https://ncbi.nlm.nih.gov/pubmed/30442804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aas8961 |
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