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Synthesis of the Cytotrienin A Core via Metal Catalyzed C-C Coupling

[Image: see text] A synthetic approach to the C17-benzene ansamycins via metal catalyzed C-C coupling is described. Key bond formations include direct iridium catalyzed carbonyl crotylation from the alcohol oxidation level followed by chelation-controlled Sakurai-Seyferth dienylation to form the ste...

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Autori principali: Rössle, Michael, Del Valle, David J., Krische, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075014/
https://ncbi.nlm.nih.gov/pubmed/21323372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol200160p
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