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Organocatalytic Synthesis of Methylene-Bridged N-Heterobiaryls

A one-step synthesis of 1,1′- and 2,2′-methylene-bridged N-heterobiaryls directly from the corresponding N-heterocycles in a reaction with methylmagnesium chloride in the presence of catalytic amounts of N,N,N′N′-tetramethylethylenediamine (TMEDA) under thermal and microwave conditions is reported....

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Dades bibliogràfiques
Publicat a:Org Lett
Autors principals: Stephens, David E., Nguyen, Vu T., Chhetri, Bhuwan, Clark, Emily R., Arman, Hadi D., Larionov, Oleg V.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148643/
https://ncbi.nlm.nih.gov/pubmed/27808520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b02719
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