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Efficient synthesis of 3-sulfolenes from allylic alcohols and 1,3-dienes enabled by sodium metabisulfite as a sulfur dioxide equivalent

We present herein an efficient and practical method for a gram scale synthesis of 3-sulfolenes using sodium metabisulfite as a safe, inexpensive, and easy to handle sulfur dioxide equivalent. Diversely-substituted 3-sulfolenes can be prepared by reacting a variety of 1,3-dienes or allylic alcohols w...

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Bibliographic Details
Published in:Org Biomol Chem
Main Authors: Dang, Hang T., Nguyen, Vu T., Nguyen, Viet D., Arman, Hadi D., Larionov, Oleg V.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002768/
https://ncbi.nlm.nih.gov/pubmed/29701220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob00745d
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