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Development of a colorectal cancer 3D micro-tumor construct platform from cell lines and patient tumor biospecimens for standard-of-care and experimental drug screening

Colorectal cancer is subject to a high rate of mutations, with late stage tumors often containing many mutations. These tumors are difficult to treat, and even with the recently implemented methods of personalized medicine at modern hospitals aiming to narrow treatments, a gap still exists. Proper m...

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Detalles Bibliográficos
Publicado en:Ann Biomed Eng
Autores principales: Forsythe, Steven, Mehta, Naren, Devarasetty, Mahesh, Sivakumar, Hemamylammal, Gmeiner, William, Soker, Shay, Votanopoulos, Konstantinos, Skardal, Aleksander
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813880/
https://ncbi.nlm.nih.gov/pubmed/31020445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-019-02269-2
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