Personalized Identification of Optimal HIPEC Perfusion Protocol in Patient-Derived Tumor Organoid Platform

BACKGROUND. Chemotherapy dosing duration and perfusion temperature vary significantly in HIPEC protocols. This study investigates patient-derived tumor organoids as a platform to identify the most efficacious perfusion protocol in a personalized approach. PATIENTS AND METHODS. Peritoneal tumor tissu...

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Publicado en:Ann Surg Oncol
Main Authors: Forsythe, Steven D., Sasikumar, Shyama, Moaven, Omeed, Sivakumar, Hemamylammal, Shen, Perry, Levine, Edward A., Soker, Shay, Skardal, Aleksander, Votanopoulos, Konstantinos I.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674215/
https://ncbi.nlm.nih.gov/pubmed/32632882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-020-08790-2
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