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Model of Patient-Specific Immune-Enhanced Organoids for Immunotherapy Screening: Feasibility Study

INTRODUCTION. We hypothesized that engineering a combined lymph node/melanoma organoid from the same patient would allow tumor, stroma, and immune system to remain viable for personalized immunotherapy screening. METHODS. Surgically obtained matched melanoma and lymph node biospecimens from the same...

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Publicat a:Ann Surg Oncol
Autors principals: Votanopoulos, Konstantinos I., Forsythe, Steven, Sivakumar, Hemamylammal, Mazzocchi, Andrea, Aleman, Julio, Miller, Lance, Levine, Edward, Triozzi, Pierre, Skardal, Aleksander
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474462/
https://ncbi.nlm.nih.gov/pubmed/31858299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-019-08143-8
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