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Mining Public Toxicogenomic Data Reveals Insights and Challenges in Delineating Liver Steatosis Adverse Outcome Pathways

Exposure to chemicals contributes to the development and progression of fatty liver, or steatosis, a process characterized by abnormal accumulation of lipids within liver cells. However, lack of knowledge on how chemicals cause steatosis has prevented any large-scale assessment of the 80,000+ chemic...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: AbdulHameed, Mohamed Diwan M., Pannala, Venkat R., Wallqvist, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813744/
https://ncbi.nlm.nih.gov/pubmed/31681434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01007
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