Data-driven prediction of adverse drug reactions induced by drug-drug interactions

Abstract Background The expanded use of multiple drugs has increased the occurrence of adverse drug reactions (ADRs) induced by drug-drug interactions (DDIs). However, such reactions are typically not observed in clinical drug-development studies because most of them focus on single-drug therapies....

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Detalhes bibliográficos
Main Authors: Ruifeng Liu, Mohamed Diwan M. AbdulHameed, Kamal Kumar, Xueping Yu, Anders Wallqvist, Jaques Reifman
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-06-01
Colecção:BMC Pharmacology and Toxicology
Assuntos:
Drug-drug interactions
Adverse drug reactions
Drug-protein interactions
Synergistic drug-drug interactions
Pharmacovigilance
Acesso em linha:http://link.springer.com/article/10.1186/s40360-017-0153-6
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