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Exploiting large-scale drug-protein interaction information for computational drug repurposing

BACKGROUND: Despite increased investment in pharmaceutical research and development, fewer and fewer new drugs are entering the marketplace. This has prompted studies in repurposing existing drugs for use against diseases with unmet medical needs. A popular approach is to develop a classification mo...

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Detalhes bibliográficos
Main Authors: Liu, Ruifeng, Singh, Narender, Tawa, Gregory J, Wallqvist, Anders, Reifman, Jaques
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079911/
https://ncbi.nlm.nih.gov/pubmed/24950817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-210
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