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Aldolase‐Catalyzed Asymmetric Synthesis of N‐Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes

Nitrogen heterocycles are structural motifs found in many bioactive natural products and of utmost importance in pharmaceutical drug development. In this work, a stereoselective synthesis of functionalized N‐heterocycles was accomplished in two steps, comprising the biocatalytic aldol addition of et...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Adv Synth Catal
Egile Nagusiak: Roldán, Raquel, Hernández, Karel, Joglar, Jesús, Bujons, Jordi, Parella, Teodor, Fessner, Wolf‐Dieter, Clapés, Pere
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813633/
https://ncbi.nlm.nih.gov/pubmed/31680790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.201801530
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