Biocatalytic Aldol Addition of Simple Aliphatic Nucleophiles to Hydroxyaldehydes

[Image: see text] Asymmetric aldol addition of simple aldehydes and ketones to electrophiles is a cornerstone reaction for the synthesis of unusual sugars and chiral building blocks. We investigated d-fructose-6-phosphate aldolase from E. coli (FSA) D6X variants as catalysts for the aldol additions...

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Publicat a:ACS Catal
Autors principals: Roldán, Raquel, Hernandez, Karel, Joglar, Jesús, Bujons, Jordi, Parella, Teodor, Sánchez-Moreno, Israel, Hélaine, Virgil, Lemaire, Marielle, Guérard-Hélaine, Christine, Fessner, Wolf-Dieter, Clapés, Pere
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2018
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135579/
https://ncbi.nlm.nih.gov/pubmed/30221031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.8b02486
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