High-performance chemical- and light-inducible recombinases in mammalian cells and mice

Site-specific DNA recombinases are important genome engineering tools. Chemical- and light-inducible recombinases, in particular, enable spatiotemporal control of gene expression. However, inducible recombinases are scarce due to the challenge of engineering high performance systems, thus constraini...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Weinberg, Benjamin H., Cho, Jang Hwan, Agarwal, Yash, Pham, N. T. Hang, Caraballo, Leidy D., Walkosz, Maciej, Ortega, Charina, Trexler, Micaela, Tague, Nathan, Law, Billy, Benman, William K. J., Letendre, Justin, Beal, Jacob, Wong, Wilson W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813296/
https://ncbi.nlm.nih.gov/pubmed/31649244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12800-7
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