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High-performance chemical- and light-inducible recombinases in mammalian cells and mice
Site-specific DNA recombinases are important genome engineering tools. Chemical- and light-inducible recombinases, in particular, enable spatiotemporal control of gene expression. However, inducible recombinases are scarce due to the challenge of engineering high performance systems, thus constraini...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6813296/ https://ncbi.nlm.nih.gov/pubmed/31649244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12800-7 |
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