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3389 Coagulation Factor Xll-mediated contact system and its role in adaptive and innate immune cell movement
OBJECTIVES/SPECIFIC AIMS: The objectives of this study are to 1) expand upon the paradigm of HK-D5 accelerated immune cell chemotaxis; 2) characterize the role of FXII in murine models of immune-mediated disease using FXII KO mice and a small molecule inhibitor of FXIIa. METHODS/STUDY POPULATION: To...
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| Pubblicato in: | J Clin Transl Sci |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cambridge University Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6812876/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2019.16 |
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