A practical synthesis of a novel DPAGT1 inhibitor, aminouridyl phenoxypiperidinbenzyl butanamide (APPB) for in vivo studies

Immunotherapy that targets N-linked glycans has not yet been developed due in large part to the lack of specificity of N-linked glycans between normal and malignant cells. N-Glycan chains are synthesized by the sequential action of glycosyl transferases in the Golgi apparatus. It is an overwhelming...

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Dades bibliogràfiques
Publicat a:MethodsX
Autors principals: Mitachi, Katsuhiko, Kurosu, Shou M., Gillman, Cody D., Yun, Hyun Gi, Clemons, William M., Kurosu, Michio
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Chemistry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812346/
https://ncbi.nlm.nih.gov/pubmed/31667130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mex.2019.09.031
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