Cargando...
Sigma‐1 receptor modulates neuroinflammation associated with mechanical hypersensitivity and opioid tolerance in a mouse model of osteoarthritis pain
BACKGROUND AND PURPOSE: Osteoarthritic pain is a chronic disabling condition lacking effective treatment. Continuous use of opioid drugs during osteoarthritic pain induces tolerance and may result in dose escalation and abuse. Sigma‐1 (σ1) receptors, a chaperone expressed in key areas for pain contr...
Gardado en:
| Publicado en: | Br J Pharmacol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2019
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6811737/ https://ncbi.nlm.nih.gov/pubmed/31332781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14794 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|