טוען...
The Sigma 2 receptor promotes and the Sigma 1 receptor inhibits mu-opioid receptor-mediated antinociception
Abstract The Sigma-1 receptor (σ1R) has emerged as an interesting pharmacological target because it inhibits analgesia mediated by mu-opioid receptors (MOR), and also facilitates the development of neuropathic pain. Based on these findings, the recent cloning of the Sigma-2 receptor (σ2R) led us to...
שמור ב:
Main Authors: | , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
BMC
2020-11-01
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סדרה: | Molecular Brain |
נושאים: | |
גישה מקוונת: | http://link.springer.com/article/10.1186/s13041-020-00676-4 |
תגים: |
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