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Blockade of the Sigma-1 Receptor Relieves Cognitive and Emotional Impairments Associated to Chronic Osteoarthritis Pain

Osteoarthritis is the most common musculoskeletal disease worldwide, often characterized by degradation of the articular cartilage, chronic joint pain and disability. Cognitive dysfunction, anxiety and depression are common comorbidities that impact the quality of life of these patients. In this stu...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Carcolé, Mireia, Zamanillo, Daniel, Merlos, Manuel, Fernández-Pastor, Begoña, Cabañero, David, Maldonado, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510262/
https://ncbi.nlm.nih.gov/pubmed/31130863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00468
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