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Blockade of the Sigma-1 Receptor Relieves Cognitive and Emotional Impairments Associated to Chronic Osteoarthritis Pain

Osteoarthritis is the most common musculoskeletal disease worldwide, often characterized by degradation of the articular cartilage, chronic joint pain and disability. Cognitive dysfunction, anxiety and depression are common comorbidities that impact the quality of life of these patients. In this stu...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Carcolé, Mireia, Zamanillo, Daniel, Merlos, Manuel, Fernández-Pastor, Begoña, Cabañero, David, Maldonado, Rafael
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510262/
https://ncbi.nlm.nih.gov/pubmed/31130863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00468
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