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Structural analysis of biological targets by host:guest crystal lattice engineering

To overcome the laborious identification of crystallisation conditions for protein X-ray crystallography, we developed a method where the examined protein is immobilised as a guest molecule in a universal host lattice. We applied crystal engineering to create a generic crystalline host lattice under...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ernst, Patrick, Plückthun, Andreas, Mittl, Peer R. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811568/
https://ncbi.nlm.nih.gov/pubmed/31645583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51017-y
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