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Crystal structures of HER3 extracellular domain 4 in complex with the designed ankyrin-repeat protein D5

The members of the human epidermal growth factor receptor (HER) family are among the most intensely studied oncological targets. HER3 (ErbB3), which had long been neglected, has emerged as a key oncogene, regulating the activity of other receptors and being involved in progression and tumor escape i...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Radom, Filip, Vonrhein, Clemens, Mittl, Peer R. E., Plückthun, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248824/
https://ncbi.nlm.nih.gov/pubmed/34196609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X21006002
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