Pbp1-Interacting Protein Mkt1 Regulates Virulence and Sexual Reproduction in Cryptococcus neoformans

The Mkt1–Pbp1 complex promotes mating-type switching by regulating the translation of HO mRNA in Saccharomyces cerevisiae. Here, we performed in vivo immunoprecipitation assays and mass spectrometry analyses in the human fungal pathogen Cryptococcus neoformans to show that Pbp1, a poly(A)-binding pr...

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Publicado en:Front Cell Infect Microbiol
Autores principales: Son, Ye-Eun, Fu, Ci, Jung, Won-Hee, Oh, Sang-Hun, Kwak, Jin-Hwan, Cardenas, Maria E., Heitman, Joseph, Park, Hee-Soo
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811503/
https://ncbi.nlm.nih.gov/pubmed/31681631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00355
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