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Pbp1-Interacting Protein Mkt1 Regulates Virulence and Sexual Reproduction in Cryptococcus neoformans

The Mkt1–Pbp1 complex promotes mating-type switching by regulating the translation of HO mRNA in Saccharomyces cerevisiae. Here, we performed in vivo immunoprecipitation assays and mass spectrometry analyses in the human fungal pathogen Cryptococcus neoformans to show that Pbp1, a poly(A)-binding pr...

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Publicat a:Front Cell Infect Microbiol
Autors principals: Son, Ye-Eun, Fu, Ci, Jung, Won-Hee, Oh, Sang-Hun, Kwak, Jin-Hwan, Cardenas, Maria E., Heitman, Joseph, Park, Hee-Soo
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811503/
https://ncbi.nlm.nih.gov/pubmed/31681631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00355
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