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Pbp1-Interacting Protein Mkt1 Regulates Virulence and Sexual Reproduction in Cryptococcus neoformans

The Mkt1–Pbp1 complex promotes mating-type switching by regulating the translation of HO mRNA in Saccharomyces cerevisiae. Here, we performed in vivo immunoprecipitation assays and mass spectrometry analyses in the human fungal pathogen Cryptococcus neoformans to show that Pbp1, a poly(A)-binding pr...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Son, Ye-Eun, Fu, Ci, Jung, Won-Hee, Oh, Sang-Hun, Kwak, Jin-Hwan, Cardenas, Maria E., Heitman, Joseph, Park, Hee-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811503/
https://ncbi.nlm.nih.gov/pubmed/31681631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00355
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