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Mon1 Is Essential for Fungal Virulence and Stress Survival in Cryptococcus neoformans

Mon1 is a guanine nucleotide exchange factor subunit that activates the Ypt7 Rab GTPase and is essential for vacuole trafficking and autophagy in eukaryotic organisms. Here, we identified and characterized the function of Mon1, an ortholog of Saccharomyces cerevisiae Mon1, in a human fungal pathogen...

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Detalhes bibliográficos
Publicado no:Mycobiology
Main Authors: Son, Ye-Eun, Jung, Won-Hee, Oh, Sang-Hun, Kwak, Jin-Hwan, Cardenas, Maria E., Park, Hee-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6023253/
https://ncbi.nlm.nih.gov/pubmed/29963312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/12298093.2018.1468053
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