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739. Prediction of Cefiderocol Pharmacokinetics and Probability of Target Attainment in Pediatric Subjects for Proposing Dose Regimens
BACKGROUND: Cefiderocol is a siderophore cephalosporin discovered by Shionogi & Co., Ltd., which exhibits potent efficacy against Gram-negative carbapenem-resistant bacteria. Pediatric clinical studies are planned. Cefiderocol is mainly renally eliminated. A 2-g infusion of cefiderocol over 3 ho...
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| Udgivet i: | Open Forum Infect Dis |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6811267/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.807 |
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