613. Suppression of Daptomycin Resistance Development in Staphylococcus aureus Is a Class Effect of β-Lactams and Is Independent of Daptomycin–β Lactam Synergy

BACKGROUND: Previous studies demonstrate that adding oxacillin during daptomycin (DAP) exposure can prevent DAP resistance development in community-acquired (ST8/USA300) MRSA, presumably by preventing mprF mutation. Hospital-acquired strains, such as MRSA sequence types 5 and 239, typically have hig...

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Bibliografiske detaljer
Udgivet i:Open Forum Infect Dis
Main Authors: Miller, Christopher R, Dey, Somrita, Smolenski, Paula, Kulkarni, Pushkar S, Baines, Sarah L, David. Berti, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811192/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.682
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