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303. A Surrogate Rodent Model for Studying Hepatitis C Virus-specific CD8 T-cell Impairment and Vaccine Prevention

BACKGROUND: Virus-specific CD8 T cells are essential for control of acute hepatitis C virus (HCV) infections, yet spontaneously fail in most patients leading to lifelong chronicity and increased risk for severe liver diseases. Efforts to study HCV-specific CD8 T-cell impairment have been hampered by...

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Bibliographic Details
Published in:Open Forum Infect Dis
Main Authors: Hartlage, Alex S, Kapoor, Amit
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6809999/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.376
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