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1532. Population Pharmacokinetic (PPK) Modeling and Simulation of Long-Acting (LA) Cabotegravir (CAB) to Inform Strategies Following Dosing Interruptions in HIV-1-Infected Subjects

BACKGROUND: CAB is an integrase strand transfer inhibitor under investigation as an injectable LA formulation for the treatment and prevention of HIV, and as a tablet formulation as an oral lead-in (OLI) and bridging treatment for dose interruptions. The monthly injection regimen of CAB LA and rilpi...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Han, Kelong, Baker, Mark, Patel, Parul, Margolis, David, Spreen, William, Moore, Katy P, Ford, Susan L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6809782/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.1396
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