2495. Pharmacokinetics of Cabotegravir (CAB) and Rilpivirine (RPV) Long-Acting (LA) Injectables in HIV-infected Individuals through 48 Weeks in the FLAIR and ATLAS Phase 3 Studies

BACKGROUND: Monthly injectable CAB LA + RPV LA was noninferior to daily oral 3-drug antiretroviral therapy in HIV-1 virologically suppressed adults. CAB and RPV pharmacokinetics (PK) were assessed during the 48 Week maintenance period of the ATLAS and FLAIR Phase 3 studies. METHODS: Patients receive...

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Publicado no:Open Forum Infect Dis
Main Authors: Patel, Parul, Ford, Susan L, Crauwels, Herta, Han, Kelong, Rossenu, Stefaan, Neyens, Martine, Griffith, Sandy, Hudson, Krischan J, Margolis, David, Baker, Mark, Williams, Peter, Spreen, William
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6809519/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.2173
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