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3502 Stimulating iNKT Cell-Mediated Neuroblastoma Cytotoxicity in a Mouse Model

OBJECTIVES/SPECIFIC AIMS: Overall Research Aim: To develop an iNKT-cell engaging reagent (“CAb”)to induce neuroblastoma-directed cytotoxicity in vitro and in a mouse model of neuroblastoma. Objective 1: Explore the contribution of different GD2 affinities to the cytotoxicity against neuroblastoma ce...

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Detalhes bibliográficos
Publicado no:J Clin Transl Sci
Main Authors: McNerney, Kevin Owen, Bassiri, Hamid, Karageorgos, Spyridon, Khurana, Priya
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6808287/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2019.53
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