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Lipid‐lowering response of the HMG‐CoA reductase inhibitor fluvastatin is influenced by polymorphisms in the low‐density lipoprotein receptor gene in Brazilian patients with primary hypercholesterolemia

Although the efficacy of fluvastatin (HMG‐CoA reductase inhibitor) in the treatment of primary hypercholesterolemia is well documented, a wide interindividual variation treatment response has been observed. We have studied the possible role of the AvaII (exon 13), HincII (exon 12), and PvuII (intron...

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Dettagli Bibliografici
Pubblicato in:J Clin Lab Anal
Autori principali: Salazar, Luis A., Hirata, Mario H., Quintão, Éder C.R., Hirata, Rosario D.C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6807834/
https://ncbi.nlm.nih.gov/pubmed/10797611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/(SICI)1098-2825(2000)14:3<125::AID-JCLA7>3.0.CO;2-S
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