Lipid‐lowering response of the HMG‐CoA reductase inhibitor fluvastatin is influenced by polymorphisms in the low‐density lipoprotein receptor gene in Brazilian patients with primary hypercholesterolemia

Although the efficacy of fluvastatin (HMG‐CoA reductase inhibitor) in the treatment of primary hypercholesterolemia is well documented, a wide interindividual variation treatment response has been observed. We have studied the possible role of the AvaII (exon 13), HincII (exon 12), and PvuII (intron...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Salazar, Luis A., Hirata, Mario H., Quintão, Éder C.R., Hirata, Rosario D.C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2000
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6807834/
https://ncbi.nlm.nih.gov/pubmed/10797611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/(SICI)1098-2825(2000)14:3<125::AID-JCLA7>3.0.CO;2-S
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