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Detection of apoB‐100 R3500Q mutation by competitive allele‐specific polymerase chain reaction
The apolipoprotein B‐100 mutation R3500Q is one of the most common inherited defects causing abnormality of the lipid metabolism. We describe a one‐step, single‐tube PCR technique for detection of the mutation based on competition between allele‐specific primers. Three oligonucleotides are used: two...
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| Publicado no: | J Clin Lab Anal |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6807702/ https://ncbi.nlm.nih.gov/pubmed/11574954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.1037 |
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