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A Human ApoB100 Transgenic Mouse expresses human ApoB100 in the RPE and develops features of early AMD
ApoB100 lipoprotein particles have been found to accumulate in Bruch membrane prior to the development of Age-related macular degeneration (AMD). This work was performed to determine whether mice that overexpress apoB100 in the RPE-choroid and liver develop landmarks of early AMD over time. Mice tra...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729121/ https://ncbi.nlm.nih.gov/pubmed/19450445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2009.01.017 |
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