A reduced form of nicotinamide riboside defines a new path for NAD(+) biosynthesis and acts as an orally bioavailable NAD(+) precursor

OBJECTIVE: A decay in intracellular NAD(+) levels is one of the hallmarks of physiological decline in normal tissue functions. Accordingly, dietary supplementation with NAD(+) precursors can prevent, alleviate, or even reverse multiple metabolic complications and age-related disorders in diverse mod...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Giroud-Gerbetant, Judith, Joffraud, Magali, Giner, Maria Pilar, Cercillieux, Angelique, Bartova, Simona, Makarov, Mikhail V., Zapata-Pérez, Rubén, Sánchez-García, José L., Houtkooper, Riekelt H., Migaud, Marie E., Moco, Sofia, Canto, Carles
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6807296/
https://ncbi.nlm.nih.gov/pubmed/31767171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.09.013
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