Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

Nicotinamide riboside (NR) is in wide use as an NAD(+) precursor vitamin. Here we determine the time and dose-dependent effects of NR on blood NAD(+) metabolism in humans. We report that human blood NAD(+) can rise as much as 2.7-fold with a single oral dose of NR in a pilot study of one individual,...

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Udgivet i:Nat Commun
Main Authors: Trammell, Samuel A. J., Schmidt, Mark S., Weidemann, Benjamin J., Redpath, Philip, Jaksch, Frank, Dellinger, Ryan W., Li, Zhonggang, Abel, E. Dale, Migaud, Marie E., Brenner, Charles
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062546/
https://ncbi.nlm.nih.gov/pubmed/27721479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12948
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