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Prevalence of abacavir-associated hypersensitivity syndrome and HLA-B*5701 allele in a Portuguese HIV-positive population

BACKGROUND: Human Immunodeficiency Virus (HIV)-positive patients treated with the antiretroviral drug abacavir (ABC) may develop a potentially fatal ABC-associated hypersensitivity syndrome (ABC-HS), typically characterized by fever, malaise, rash, vomiting/diarrhoea and/or dyspnoea/cough. ABC-HS ha...

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Vydáno v:Porto Biomed J
Hlavní autoři: Carolino, Fabrícia, Santos, Natacha, Piñeiro, Carmela, Santos, Ana Sofia, Soares, Pedro, Sarmento, António, Cernadas, Josefina Rodrigues
Médium: Artigo
Jazyk:Inglês
Vydáno: Faculty of Medicine of the University of Porto 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6806971/
https://ncbi.nlm.nih.gov/pubmed/32258586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbj.2016.12.004
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