Prevalence of HLA-B*5701 and Its Relationship with Abacavir Hypersensitivity Reaction in Iranian HIV-Infected Patients

BACKGROUND: Hypersensitivity reaction (HSR) is a major adverse effect of abacavir (ABC), which occurs in 5–8% of Caucasians. The relationship between Human Leukocyte Antigen (HLA) and ABC HSR has been reported in various populations. It has been proposed to administer ABC only to HLA-B*5701 negative...

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Udgivet i:Tanaffos
Main Authors: Baniasadi, Shadi, Shokouhi, Shokoufeh Baradaran, Tabarsi, Payam, Alehashem, Maryam, Khalili, Hossein, Fahimi, Fanak, Nadji, Seyed Alireza
Format: Artigo
Sprog:Inglês
Udgivet: National Research Institute of Tuberculosis and Lung Disease 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937762/
https://ncbi.nlm.nih.gov/pubmed/27403179
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