Tibial post fracture pain is reduced in kinin receptors deficient mice and blunted by kinin receptor antagonists

BACKGROUND: Tibial fracture is associated with inflammatory reaction leading to severe pain syndrome. Bradykinin receptor activation is involved in inflammatory reactions, but has never been investigated in fracture pain. METHODS: This study aims at defining the role of B1 and B2-kinin receptors (B1...

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Veröffentlicht in:J Transl Med
Hauptverfasser: Minville, Vincent, Mouledous, Lionel, Jaafar, Acil, Couture, Réjean, Brouchet, Anne, Frances, Bernard, Tack, Ivan, Girolami, Jean-Pierre
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805420/
https://ncbi.nlm.nih.gov/pubmed/31640792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-2095-9
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